240.13d-102 Schedule 13G - Information to be included in statements filed
pursuant to 240.13d-1(b), (c), and (d) and amendments thereto
filed pursuant to 240.13d-2.
Securities and Exchange Commission, Washington, D.C. 20549
Schedule 13G
Under the Securities Exchange Act of 1934
(Amendment No. 1)*
(Name of Issuer)
Applied Therapeutics, Inc.
(Title of Class of Securities)
Common Stock, par value $0.0001 per share
(CUSIP Number)
03828A101
(Date of Event Which Requires Filing of this Statement)
December 31, 2022
Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
[ ] Rule 13d-1(b)
[ x ] Rule 13d-1(c)
[ ] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be
deemed to be “filed” for the purpose of Section 18 of the Securities Exchange
Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, see
the Notes).
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be
deemed to be “filed” for the purpose of Section 18 of the Securities Exchange
Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, see
the Notes).
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CUSIP No. 03828A101
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(1) Names of reporting persons Point72 Asset Management, L.P.
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(2) Check the appropriate box if a member of a group
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(a)
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(see instructions)
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(b)X
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(3) SEC use only
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(4) Citizenship or place of organization Delaware
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Number of shares beneficially owned by each reporting person with:
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(5) Sole voting power 0
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(6) Shared voting power 719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(7) Sole dispositive power 0
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(8) Shared dispositive power 719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(9) Aggregate amount beneficially owned by each reporting person
719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(10) Check if the aggregate amount in Row (9) excludes certain shares
(see instructions)
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(11) Percent of class represented by amount in Row (9) 3.2% (see Item 4)
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(12) Type of reporting person (see instructions) PN
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CUSIP No. 03828A101
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(1) Names of reporting persons Point72 Capital Advisors, Inc.
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(2) Check the appropriate box if a member of a group
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(a)
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(see instructions)
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(b)X
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(3) SEC use only
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(4) Citizenship or place of organization Delaware
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Number of shares beneficially owned by each reporting person with:
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(5) Sole voting power 0
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(6) Shared voting power 719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(7) Sole dispositive power 0
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(8) Shared dispositive power 719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(9) Aggregate amount beneficially owned by each reporting person
719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(10) Check if the aggregate amount in Row (9) excludes certain shares
(see instructions)
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(11) Percent of class represented by amount in Row (9) 3.2% (see Item 4)
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(12) Type of reporting person (see instructions) CO
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CUSIP No. 03828A101
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(1) Names of reporting persons Cubist Systematic Strategies, LLC
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(2) Check the appropriate box if a member of a group
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(a)
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(see instructions)
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(b)X
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(3) SEC use only
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(4) Citizenship or place of organization Delaware
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Number of shares beneficially owned by each reporting person with:
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(5) Sole voting power 0
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(6) Shared voting power 0
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(7) Sole dispositive power 0
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(8) Shared dispositive power 0
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(9) Aggregate amount beneficially owned by each reporting person
0
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(10) Check if the aggregate amount in Row (9) excludes certain shares
(see instructions)
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(11) Percent of class represented by amount in Row (9) 0%
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(12) Type of reporting person (see instructions) OO
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CUSIP No. 03828A101
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(1) Names of reporting persons Point72 Hong Kong Limited
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(2) Check the appropriate box if a member of a group
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(a)
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(see instructions)
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(b)X
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(3) SEC use only
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(4) Citizenship or place of organization Hong Kong
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Number of shares beneficially owned by each reporting person with:
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(5) Sole voting power 0
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(6) Shared voting power 0
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(7) Sole dispositive power 0
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(8) Shared dispositive power 0
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(9) Aggregate amount beneficially owned by each reporting person
0
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(10) Check if the aggregate amount in Row (9) excludes certain shares
(see instructions)
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(11) Percent of class represented by amount in Row (9) 0%
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(12) Type of reporting person (see instructions) OO
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CUSIP No. 03828A101
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(1) Names of reporting persons Steven A. Cohen
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(2) Check the appropriate box if a member of a group
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(a)
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(see instructions)
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(b)X
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(3) SEC use only
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(4) Citizenship or place of organization United States
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Number of shares beneficially owned by each reporting person with:
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(5) Sole voting power 0
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(6) Shared voting power 719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(7) Sole dispositive power 0
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(8) Shared dispositive power 719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(9) Aggregate amount beneficially owned by each reporting person
719,938 shares of Common Stock
830,000 shares of Common Stock issuable upon exercise of Warrants
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(10) Check if the aggregate amount in Row (9) excludes certain shares
(see instructions)
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(11) Percent of class represented by amount in Row (9) 3.2% (see Item 4)
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(12) Type of reporting person (see instructions) IN
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Item 1(a) Name of issuer:
Applied Therapeutics, Inc.
Item 1(b) Address of issuer's principal executive offices:
545 Fifth Avenue, Suite 1400, New York, New York 10017
2(a) Name of person filing:
This statement is filed by: (i) Point72 Asset Management, L.P. (“Point72 Asset Management”) with respect to shares of common stock, par value $0.0001 per share (“Common Stock”), of
the Issuer held by (and issuable upon exercise of warrants held by) an investment fund it manages; (ii) Point72 Capital Advisors, Inc. (“Point72 Capital Advisors Inc.”) with respect to Common Stock held by (and issuable upon exercise of warrants
held by) an investment fund managed by Point72 Asset Management; (iii) Cubist Systematic Strategies, LLC (“Cubist Systematic Strategies”) with respect to Common Stock held by an investment fund it manages; (iv) Point72 Hong Kong Limited (“Point72
Hong Kong”) with respect to Common Stock held by an investment fund it manages; and (v) Steven A. Cohen (“Mr. Cohen”) with respect to Common Stock beneficially owned by Point72 Asset Management, Point72 Capital Advisors Inc., Cubist Systematic
Strategies, and Point72 Hong Kong.
2(b) Address or principal business office or, if none, residence:
The address of the principal business office of (i) Point72 Asset Management, Point72 Capital Advisors Inc., and Mr. Cohen is 72 Cummings Point Road, Stamford, CT 06902; (ii) Cubist
Systematic Strategies is 55 Hudson Yards, New York, NY 10001; and (iii) Point72 Hong Kong is Suites 1102 – 1110, 11th Floor and 12th Floor, Chater House, 8 Connaught Road Central, Hong Kong.
2(c) Citizenship:
Point72 Asset Management is a Delaware limited partnership. Point72 Capital Advisors Inc. is a Delaware corporation. Cubist Systematic Strategies is a Delaware limited liability
company. Point72 Hong Kong is a Hong Kong limited liability company. Mr. Cohen is a United States citizen.
2(d) Title of class of securities:
Common Stock, par value $0.0001 per share
2(e) CUSIP Number:
03828A101
Item 3.
Not applicable
Item 4. Ownership
The information required by Items 4(a) – (c) is set forth in Rows (5) – (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person. Such information is as of
the close of business on December 31, 2022
Point72 Asset Management, Point72 Capital Advisors Inc., Cubist Systematic Strategies, Point72 Hong Kong, and Mr. Cohen own directly no Common Stock. Pursuant to an investment
management agreement, Point72 Asset Management maintains investment and voting power with respect to the securities held by an investment fund it manages. Point72 Capital Advisors Inc. is the general partner of Point72 Asset Management. Pursuant to
an investment management agreement, Cubist Systematic Strategies maintains investment and voting power with respect to the securities held by an investment fund it manages. Pursuant to an investment management agreement, Point72 Hong Kong maintains
investment and voting power with respect to the securities held by an investment fund it manages. Mr. Cohen controls each of Point72 Asset Management, Point72 Capital Advisors Inc., Cubist Systematic Strategies, and Point72 Hong Kong. The filing
of this statement should not be construed as an admission that any of the foregoing persons or any reporting person is, for the purposes of Section 13 of the Act, the beneficial owner of the Common Stock reported herein.
The percentage set forth in Row 11 of the cover page for each Reporting Person is based on 48,058,965 shares of Common Stock issued and outstanding as of November 8, 2022, as
represented in the Company’s Quarterly Report filed with the Securities and Exchange Commission on November 9, 2022; plus 830,000 shares of Common Stock issuable upon exercise of Warrants.
Item 5. Ownership of 5 Percent or Less of a Class.
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following [X].
Item 6. Ownership of More than 5 Percent on Behalf of Another Person.
See Item 2(a)
Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reporting on by the Parent Holding Company or Control Person.
Not applicable
Item 8. Identification and Classification of Members of the Group
Not applicable
Item 9. Notice of Dissolution of Group.
Not applicable
Item 10. Certifications
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of
the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.
Signature. After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Dated: February 14, 2023
POINT72 ASSET MANAGEMENT, L.P.
By: /s/ Jason M. Colombo
Name: Jason M. Colombo
Title: Authorized Person
Name: Jason M. Colombo
Title: Authorized Person
POINT72 CAPITAL ADVISORS, INC.
By: /s/ Jason M. Colombo
Name: Jason M. Colombo
Title: Authorized Person
Name: Jason M. Colombo
Title: Authorized Person
CUBIST SYSTEMATIC STRATEGIES, LLC
By: /s/ Jason M. Colombo
Name: Jason M. Colombo
Title: Authorized Person
POINT72 HONG KONG LIMITED
Name: Jason M. Colombo
Title: Authorized Person
POINT72 HONG KONG LIMITED
By: /s/ Jason M. Colombo
Name: Jason M. Colombo
Title: Authorized Person
STEVEN A. COHEN
Name: Jason M. Colombo
Title: Authorized Person
STEVEN A. COHEN
By: /s/ Jason M. Colombo
Name: Jason M. Colombo
Title: Authorized Person
Name: Jason M. Colombo
Title: Authorized Person